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The use of AACSB accreditation as an indicator of
2019-11-28
The use of AACSB accreditation as an indicator of expected performance on the CPA exam has been examined by prior studies (e.g. Barilla et al., 2008, Boone et al., 2006, Grant et al., 2002, Howell and Heshizer, 2006, Lindsay and Campbell, 2003, Marts et al., 1998). While these studies are based on d
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The quantification and monitoring of ChEs enzymatic activiti
2019-11-28
The quantification and monitoring of ChEs enzymatic activities have traditionally been associated to environmental studies in order to diagnose the exposure of non-target organisms to specific anti-cholinesterasic agents (Nunes, 2011). The importance of these enzymes as biomarkers of environmental c
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br Results br Discussion We
2019-11-28
Results Discussion We first tested for any adverse effect of ATR on learning and memory with a MWM test, which is used to assess hippocampal spatial learning and memory abilities in rodents (Vorhees and Williams, 2006). In the place navigation test, the escape latency – or time spent locating
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In summary we elucidated the
2019-11-28
In summary, we elucidated the in vitro activities of KDM1B in regulation of PC cell proliferation and apoptosis. These studies provided a novel insight into the previously unrecognized roles of KDM1B in human PC cells. We showed for the first time that KDM1B knockdown attenuated proliferation and in
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Employing distinct genetic and pharmacological approaches Di
2019-11-28
Employing distinct genetic and pharmacological approaches, Divakaruni et al. now demonstrate that macrophages still acquire their IL-4-elicited phenotype in the absence of CPT1a (considered the main isoform in leukocytes) or CPT2, and highlight that the increased LC-FAO in M(IL-4) cells is less cruc
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The effect of the simple dopaminergic tonic
2019-11-28
The effect of the simple dopaminergic tonic/phasic model on cognitive processing has been investigated by a few studies (Nolan et al., 2004; Rosa et al., 2010). Rosa et al. (2010), using a Stroop task that requires different levels of cognitive flexibility and stability, observed an association betw
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ion channel Our finding that VEGF A induced
2019-11-27
Our finding that VEGF-A induced downregulation of EphB4 is VEGFR2 dependent (Fig. 4A) is not surprising because VEGFR2 is the primary signaling receptor of VEGF-A in EC [34]. However, our finding that VEGF-A induced upregulation of dll4 ion channel is not inhibited by VEGFR2 inhibition suggests tha
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The data from the Sur lab have
2019-11-27
The data from the Sur lab have showed DNA-PK is involved in metabolic gene regulation in response to insulin. DNA-PK regulates fatty hydrochloride mg synthesis by modulating the protein expression of fatty acid synthase (FAS) in a feeding-dependent manner. DNA-PK induces the activation of Upstream
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In the present study we
2019-11-27
In the present study, we implemented the dendritic RCA-induced formation of amplifying DNAzyme catalytic labels strategy for sensitive and accurate assay of MTase activity and the detection of DNA methylation. In comparison with the traditional RCA process, the proposed strategy achieved high amplif
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The larger eukaryotic ligases such as LigI and LigIV also
2019-11-27
The larger eukaryotic ligases, such as LigI and LigIV, also possess an additional N-terminal DNA-binding domain (DBD) that is required for efficient ligation (Fig. 1c) and enables these ligases to encircle DNA [17]. An equivalent helix–hairpin–helix domain is also present in the bacterial NAD-depend
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The identification of a gatekeeper mutation also suggests
2019-11-27
The identification of a gatekeeper BMS-754807 sale also suggests that alternative DDR2 inhibitors may be required to overcome acquired resistance. Additional DDR2 inhibitors that have been isolated include the recently identified alkaloid natural products discoipyrroles A-D and the chemotherapeutic
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Crystal structures of various CRM complexes have provided in
2019-11-27
Crystal structures of various CRM1 complexes have provided insight into molecular details of the interactions between CRM1 and its interaction partners during the transport cycle. CRM1 cooperatively binds RanGTP and cargo in the nucleus (Paraskeva et al., 1999). In this ternary complex, RanGTP is lo
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The consistent anti anxiety effects obtained with
2019-11-27
The consistent anti-anxiety effects obtained with intra-mPFC injections of CP 376395 strongly suggest a tonic role of CRF at CRF1 receptors located within this limbic egfr inhibitors area in the modulation of anxiety in the mouse on the EPM. Intra-mPFC injection of CP 376395 led mice to explore the
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A limitation of this study is the between study heterogeneit
2019-11-27
A limitation of this study is the between-study heterogeneity of the datasets analyzed. To address this heterogeneity, we used a random-effects model in our analysis. Also, only 2 of the databases provided information on sex, and as a result, the sex-specific analyses were performed with a smaller c
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Carbonization and decarbonation are two different phases in
2019-11-27
Carbonization and decarbonation are two different phases in the decomposition of rice husk. Silica in RHA melts around 1440°C [5]. Burning of rice husk at temperature lower than 800°C produces reactive amorphous silica which contains approximately 90% silica, whereas above this temperature some crys
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