• br Martyn Plummer and colleagues September analyse the

  2019-04-19

  

  Martyn Plummer and colleagues (September, 2016) analyse the global burden of cancers attributable to infections in 2012. Despite the relatively low attributable proportion compared with other infectious agents, liver flukes, including and , were estimated to have caused 1300 new cases of cholangio

• br Methods br Results br Discussion br Conclusions br Confli

  2019-04-19

  

  Methods Results Discussion Conclusions Conflict of interest statement Introduction The origin of a nonsustained ventricular tachycardia (NSVT) can usually be estimated with the 12-lead electrocardiogram (ECG) [1–3]; however, anatomical abnormalities sometimes make it difficult to

• rubbish The clinical presentation of patients with CIED pock

  2019-04-19

  

  The clinical presentation of patients with CIED pocket infection and those with endovascular infection can vary, but once the diagnosis is made, the management is similar and involves removal of all hardware along with antibiotic therapy [2,7,8,15]. Conservative managements with rubbish therapy onl

• br Conflict of interest br

  2019-04-19

  

  Conflict of interest Introduction Baseline ablation strategies targeting PVs It is well known that PVI was first developed to eliminate the triggers that initiate attacks of paroxysmal atrial fibrillation [1]. Subsequently, the additional function of the PV myocardium to perpetuate atrial f

• br Patients and methods br

  2019-04-19

  

  Patients and methods Discussion In this matrix metalloproteinases secondary endpoint analysis of the OPTION trial, we have shown that the addition of goserelin to neo(adjuvant) chemotherapy temporarily increased bone turnover during treatment and that this reverses over the next 6–12 months a

• Studies and reports of lung

  2019-04-19

  

  Studies and reports of lung Epothilone B of GCTB are rare because of the low incidence of lung metastasis. The biological behavior and clinical features of GCTB are difficult to predict [6,7]. Some researchers have attempted to analyze related clinical factors of lung metastasis, such as age, sex,

• Cholangiopathies are a group of rare diseases

  2019-04-19

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• br Role of dysfunctional telomeres

  2019-04-18

  

  Role of dysfunctional telomeres in activation of p38 MAPK pathway as response to genotoxic stress Telomeres are unique structures at the ends of chromosomes that are located adjacent to more gene rich sub-telomeric regions and comprised of tandem GT-rich repeats, (TTAGGG)n in humans and other ver

• HBV DNA levels are associated with

  2019-04-18

  

  HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo

• There has been scant prior research focusing

  2019-04-18

  

  There has been scant prior research focusing on the clinical efficiency and safety of either BV alone or in combination with chemotherapy in treating relapsed or refractory CD30+ T cell lymphoma, ALCL and HL. Although the most common and significant adverse events of BV, such as peripheral neuropath

• In patients with ovary lesions

  2019-04-18

  

  In patients with ovary lesions, surgical intervention play an important role to establish correct diagnosis. First of all, obtaining histologic confirmation of disease by laparotomy is critical in differentiating primary ovarian cancer between metastatic lesions such as gastric cancer to the ovary (

• Your support for the official journal of the Japan Heart

  2019-04-18

  

  Your support for the , official journal of the Japan Heart Rhythm Society (JHRS) and the Asia Pacific Heart Rhythm Society (APHRS), is sincerely appreciated. We are pleased to announce that JOA has become an open access journal. Thus it is always available for readers online. All articles are acces

• In addition to inducing IKs

  2019-04-18

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• NVP-BKM120 cost In the present study the

  2019-04-18

  

  In the present study, the timing of the LA potentials in respect to the timing of the CSM potentials depended closely on the direction of impulse propagation across the interatrial connection at the proximal CS. Thus, a LA → CSM activation sequence was observed only when the wavefront traveled throu

• br Possible reasons for the divergent results for the

  2019-04-18

  

  Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site

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