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In the current era nearly all cases of
2019-05-10

In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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FD appears radiographically as radiolucent
2019-05-10

FD appears radiographically as radiolucent areas which later develop into a partially opaque ground glass appearance [51]. Other features that may be present are endosteal scalloping, bony expansion, and a thick reactive bone ‘rind’ [54]. MR imaging may be a more effective tool at identifying the si
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find more br Material and methods br Results
2019-05-10

Material and methods Results Discussion PV isolation is currently the cornerstone for treatment of patients with paroxysmal AF [6]. An extended technique is circumferential PV isolation using point-by-point ablation around the PV ostium. However, that is a technically challenging and time-c
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In silico prediction software SIFT PolyPhen
2019-05-10

In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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Mismo fen meno se observa
2019-05-10

Mismo fenómeno se observa en El Museo Mexicano, publicación ciertamente exitosa y donde se dieron cita los escritores más sobresalientes de la literatura mexicana decimonónica entre los años 1843 hasta 1846. El epígrafe que remata la portada constituye, en términos programáticos, todo una declaració
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br Although killed whole cell oral cholera vaccines OCVs
2019-05-10

Although killed, whole-cell oral cholera vaccines (OCVs) have been known to be efficacious since 1986, and the bivalent whole-cell vaccine Shanchol has been licensed in India since 2009, OCV was not regarded as useful for controlling cholera outbreaks until recently. Many public health officials q
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El otro paradigma cuyo alcance y magnitud exige
2019-05-10

El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso rad51 inhibitor la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de figuras como Irlem
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br Disclosures br Acknowledgments This study was
2019-05-10

Disclosures Acknowledgments This study was supported by the Austrian National Science Fund (FWF), Grant # SFB-F4704. Introduction Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Extramedullary involvement of the kidneys is seen in around 7% when assessed by in
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br Panels A to D show intracardiac recordings of
2019-05-10

Panels A to D show intracardiac recordings of the HRA extrastimuli with A1A2 intervals of 320−290ms at a basic CL of 600ms. The AV conduction intervals were increased gradually rather than suddenly, so that an Ae with an A2–V2–Ae sequence could be provoked only at 310ms and 300ms, followed by no A
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br Materials and methods br Results br Discussion Although
2019-05-09

Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between E
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br Conclusion Our findings may help physicians in
2019-05-09

Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic SAR405 is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it may n
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br Results Twenty seven bone lesions
2019-05-09

Results Twenty-seven bone lesions were analyzed in 27 patients. Twelve of the patients were female and 15 were male. The mean age of the patients was 58 years with a range of 21–84 years. Ten lesions were determined to be malignant and 17 benign. Benign lesions of bone dropped in signal on out-of
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br Results There were cases where cryotherapy was used
2019-05-09

Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors
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br Materials and methods Eculizumab levels were
2019-05-09

Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)
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In acute ventricular perforations the lead
2019-05-09

In acute ventricular perforations, the lead can be repositioned and followed with serial echocardiograms to monitor resolution of perforation and to detect deterioration that would require immediate intervention. In the subacute and delayed perforations, if there is no bleeding in the mediastinum, t
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