• Education is part of the foundation for a

  2019-05-13

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres

• Dyslipidemia is characterized by increased total cholesterol

  2019-05-13

  

  Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The

• br Methods br Results br Discussion br

  2019-05-10

  

  Methods Results Discussion Conclusions Conflict of interest Acknowledgments We thank Mr. John Martin for his linguistic assistance, and Mr. Jiro Suto for technical assistance in developing the QRS-T subtraction program. This study was supported by the Fukuda Foundation for Medical

• We herein report a patient with dMMR

  2019-05-10

  

  We herein report a patient with dMMR and MSI-H metastatic gastric cancer who full read responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockade. Res

• In the current era nearly all cases of

  2019-05-10

  

  In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud

• FD appears radiographically as radiolucent

  2019-05-10

  

  FD appears radiographically as radiolucent areas which later develop into a partially opaque ground glass appearance [51]. Other features that may be present are endosteal scalloping, bony expansion, and a thick reactive bone ‘rind’ [54]. MR imaging may be a more effective tool at identifying the si

• find more br Material and methods br Results

  2019-05-10

  

  Material and methods Results Discussion PV isolation is currently the cornerstone for treatment of patients with paroxysmal AF [6]. An extended technique is circumferential PV isolation using point-by-point ablation around the PV ostium. However, that is a technically challenging and time-c

• In silico prediction software SIFT PolyPhen

  2019-05-10

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• Mismo fen meno se observa

  2019-05-10

  

  Mismo fenómeno se observa en El Museo Mexicano, publicación ciertamente exitosa y donde se dieron cita los escritores más sobresalientes de la literatura mexicana decimonónica entre los años 1843 hasta 1846. El epígrafe que remata la portada constituye, en términos programáticos, todo una declaració

• br Although killed whole cell oral cholera vaccines OCVs

  2019-05-10

  

  Although killed, whole-cell oral cholera vaccines (OCVs) have been known to be efficacious since 1986, and the bivalent whole-cell vaccine Shanchol has been licensed in India since 2009, OCV was not regarded as useful for controlling cholera outbreaks until recently. Many public health officials q

• El otro paradigma cuyo alcance y magnitud exige

  2019-05-10

  

  El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso rad51 inhibitor la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de figuras como Irlem

• br Disclosures br Acknowledgments This study was

  2019-05-10

  

  Disclosures Acknowledgments This study was supported by the Austrian National Science Fund (FWF), Grant # SFB-F4704. Introduction Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Extramedullary involvement of the kidneys is seen in around 7% when assessed by in

• br Panels A to D show intracardiac recordings of

  2019-05-10

  

  Panels A to D show intracardiac recordings of the HRA extrastimuli with A1A2 intervals of 320−290ms at a basic CL of 600ms. The AV conduction intervals were increased gradually rather than suddenly, so that an Ae with an A2–V2–Ae sequence could be provoked only at 310ms and 300ms, followed by no A

• br Materials and methods br Results br Discussion Although

  2019-05-09

  

  Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between E

• br Conclusion Our findings may help physicians in

  2019-05-09

  

  Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic SAR405 is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it may n

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