• Similar to HF myocardial infarction MI is followed by

  2019-05-27

  

  Similar to HF, myocardial infarction (MI) is followed by significant down-regulation of multiple K currents in the peri-infarct zone. These changes may contribute to after-depolarization and ventricular arrhythmia in MI ventricles. However, none of the previous studies reported MI in an increased IK

• ccr5 antagonist What lies ahead Clearly the extremely ambiti

  2019-05-24

  

  What lies ahead? Clearly the extremely ambitious goals and targets set by the UNCoLSC have not been reached, and challenges must be overcome. While the current evaluation highlights several challenges and strategies for action, a clear process in moving forward would be to link this bottleneck analy

• influenza a virus Introduction Atrial fibrillation AF is the

  2019-05-24

  

  Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia managed in clinical practice and the most common arrhythmia requiring hospitalization [1,2]. Thromboembolism occurs with similar incidence, regardless of the form of AF [3,4]. AF management includes anticoagulation to preve

• br Over the past decade global

  2019-05-24

  

  Over the past decade, global concern about the disproportionate burden of disease and mortality in low-income countries, especially in sub-Saharan Africa, has led to a substantial influx of funding for research by many donor and research agencies. This investment has energised in-country research;

• This population based study demonstrates

  2019-05-24

  

  This population-based study demonstrates that interventions must change attitudes regarding violence in the home and society, promote positive parenting practices, and tackle the inequality that allows the normalisation of violence and patriarchal power over women and children. Violence does not occ

• Patients were divided randomly into two groups at

  2019-05-24

  

  Patients were divided randomly into two groups at the time of hCG administration. Patients in Group 1 (n = 38; 33.6%) underwent IUI 24 hours after hCG administration. Group 2 (n = 75; 66.4%) underwent IUI 36 hours after hCG administration. All patients were instructed to have intercourse when the do

• Another problem is that the indications of each

  2019-05-24

  

  Another problem is that the indications of each drug differ among Asia-Pacific countries, and it ion channels is difficult to provide recommendations that are consistent with the indications in each country. For example, in Japan, the 3 novel OACs are indicated for “the prevention of ischemic strok

• Importance of heart failure Acute decompensated heart failur

  2019-05-24

  

  Importance of lipoxygenase inhibitor failure Acute decompensated heart failure (ADHF) refers to a clinical condition of worsening HF with dyspnea, often with evidence of fluid overload [1]. This is generally triggered by 1 of the 4 main factors: atrial fibrillation, anemia, hypertension, and medic

• dofetilide Introduction Multiple myeloma MM is the most freq

  2019-05-24

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• br Epigenetic regulation of genes involved in hepatic lipid

  2019-05-24

  

  Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl

• br In Anand Bhopal s discussion March

  2019-05-24

  

  In Anand Bhopal\'s discussion (March, 2015) of health inequalities, social determinants of health, and advocacy for social change in health care in the 21st century, we were disappointed to see little recognition of the branch of medicine that pilocarpine hydrochloride epitomises “societal doctor

• br OPG RANK and RANKL contribute to the

  2019-05-23

  

  OPG, RANK and RANKL contribute to the vicious cycle established between tumour BIBF1120 and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several argum

• Introduction The World health organization WHO defines acute

  2019-05-23

  

  Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line

• niclosamide Holter ECG monitoring was performed after the pa

  2019-05-23

  

  Holter ECG monitoring was performed after the patient consumed 180mL of sake (alcohol) each night in both the DDD-R and DDD-CLS modes. The mean HR in the DDD-CLS mode (68bpm) was similar to that (71bpm) in the DDD-R mode, but during sleep, the atrial pacing ratio (43.2%) in DDD-CLS was significantly

• The exhibited efficacies of bone targeting treatments in pha

  2019-05-23

  

  The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b

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