• br Patients and methods br

  2019-04-19

  

  Patients and methods Discussion In this matrix metalloproteinases secondary endpoint analysis of the OPTION trial, we have shown that the addition of goserelin to neo(adjuvant) chemotherapy temporarily increased bone turnover during treatment and that this reverses over the next 6–12 months a

• Studies and reports of lung

  2019-04-19

  

  Studies and reports of lung Epothilone B of GCTB are rare because of the low incidence of lung metastasis. The biological behavior and clinical features of GCTB are difficult to predict [6,7]. Some researchers have attempted to analyze related clinical factors of lung metastasis, such as age, sex,

• Cholangiopathies are a group of rare diseases

  2019-04-19

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• br Role of dysfunctional telomeres

  2019-04-18

  

  Role of dysfunctional telomeres in activation of p38 MAPK pathway as response to genotoxic stress Telomeres are unique structures at the ends of chromosomes that are located adjacent to more gene rich sub-telomeric regions and comprised of tandem GT-rich repeats, (TTAGGG)n in humans and other ver

• HBV DNA levels are associated with

  2019-04-18

  

  HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo

• There has been scant prior research focusing

  2019-04-18

  

  There has been scant prior research focusing on the clinical efficiency and safety of either BV alone or in combination with chemotherapy in treating relapsed or refractory CD30+ T cell lymphoma, ALCL and HL. Although the most common and significant adverse events of BV, such as peripheral neuropath

• In patients with ovary lesions

  2019-04-18

  

  In patients with ovary lesions, surgical intervention play an important role to establish correct diagnosis. First of all, obtaining histologic confirmation of disease by laparotomy is critical in differentiating primary ovarian cancer between metastatic lesions such as gastric cancer to the ovary (

• Your support for the official journal of the Japan Heart

  2019-04-18

  

  Your support for the , official journal of the Japan Heart Rhythm Society (JHRS) and the Asia Pacific Heart Rhythm Society (APHRS), is sincerely appreciated. We are pleased to announce that JOA has become an open access journal. Thus it is always available for readers online. All articles are acces

• In addition to inducing IKs

  2019-04-18

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• NVP-BKM120 cost In the present study the

  2019-04-18

  

  In the present study, the timing of the LA potentials in respect to the timing of the CSM potentials depended closely on the direction of impulse propagation across the interatrial connection at the proximal CS. Thus, a LA → CSM activation sequence was observed only when the wavefront traveled throu

• br Possible reasons for the divergent results for the

  2019-04-18

  

  Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site

• Furthermore permanent cardiac pacemaker implantation may

  2019-04-18

  

  Furthermore, permanent cardiac pacemaker implantation may be required when severe bradyarrhythmia recurs for a long period. Sympathetic preganglionic neurons innervating the l-ascorbic acid may be damaged beyond recovery in such cases [2]. Since placement of new leads immediately after infected lead

• br On Nov every year the International Day

  2019-04-18

  

  On Nov 25 every year, the International Day for the Elimination of Violence Against Women, and the 16 days of activism that follow it, help to draw the world\'s attention to the scourge of intimate partner violence and other forms of gender-based violence and their harmful effects on women\'s heal

• Assim como forma de ep logo

  2019-04-18

  

  Assim, como forma de epílogo que ligue essa ideia central defendida por nós, citamos o editorial de lançamento da revista Araucaria de Chile, que, em 1978, afirmava: Bien se sabe que Chile no es una isla ni su tragedia combate un accidente ni un caso de excepción en América Latina. Su situación se

• br INTRODUCCI N Con la incorporaci n de los

  2019-04-18

  

  INTRODUCCIÓN Con la incorporación de los derechos colectivos de los pueblos indígenas en la normatividad internacional de los derechos humanos, se inicia una nueva etapa en la conflictiva relación entre las bases fundacionales del poder político moderno y la diversidad cultural, en tanto aquellas

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