• For example glutamate is increasingly recognized as one

  2019-05-08

  

  For example, glutamate is increasingly recognized as one of the important dysregulated signaling molecules in cancer biology, especially in the context of bone metastasis. Commonly recognized as an excitatory neurotransmitter necessary for normal folate analogue function, glutamate is also intimate

• The results of the study are highly encouraging HIV testing

  2019-05-07

  

  The results of the study are highly encouraging. HIV testing rates were significantly higher in the intervention arm than in the control arm (92% 55%). In multivariable models, the likelihood of not receiving an HIV test was more than 11-fold greater (adjusted odds ratio 11·2, 95% CI 8·8–14·3; pand

• We also thank Kate Mandeville and Adamson Muula

  2019-05-07

  

  We also thank Kate Mandeville and Adamson Muula for their letter and agree with the need to ensure resources are available to fund salaries for newly trained doctors and other health workers to allow these workers to be absorbed into the under-resourced Malawian health system. The doctors\' salary c

• Even so the purpose of our

  2019-05-07

  

  Even so, the purpose of our Comment was to counter the notion that is useful to think in terms of “Ebola suspects” and their ostensible options, while reminding us to question whether the fetishisation of isolation over treatment was “an institutionalized form of non-assistance” that resulted in “a

• Con respecto de la importancia del

  2019-05-07

  

  Con respecto de la importancia del periodo colonial, hay dos ideas en sus reflexiones que quisiera rescatar: la primera es su consideración de esta época como el de la sociedad mexicana, pues es en esta etapa cuando se produce la “creación de una nueva sociedad”, cuyo desarrollo “presenta un materi

• br Conventional mapping and ablation of ventricular tachycar

  2019-05-07

  

  Conventional mapping and ablation of ventricular tachycardia Substrate mapping during sinus rhythm Technical issues Conclusion Conflict of interest Introduction By eliminating the arrhythmogenic focus, catheter ablation can be a curative therapy of ventricular tachyarrhythmias (VTA

• br Heart rate turbulence HRT HRT was

  2019-05-07

  

  Heart rate turbulence (HRT) HRT was introduced by Schidmt in 1999 [11]. It refers to the physiological phenomenon in response to a premature beat. After a ventricular premature contraction (VPC) and a compensatory pause, there is an increase in blood pressure because of the prolonged filling. Ref

• br Statistical power and analysis A description

  2019-05-07

  

  Statistical power and analysis A description of the statistical analysis of the study has been published previously [23]. For the analysis of the results at the 5-year time point, comparisons were expressed graphically using 95% confidence intervals. Statistical analysis was performed using SPSS

• In contrast to adults PBL in

  2019-05-07

  

  In RVX-208 cost to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is characterized by rapid progression, a

• Entre las publicaciones de indagaci n epistemol gica se

  2019-05-07

  

  Entre las publicaciones de indagación epistemológica se incluyen aquellas que plantean los cuestionamientos al pensamiento científico de la época y otras que reflexionan sobre la investigación científica, sus desarrollos y consecuencias iatrogénicas. Sobre estos particulares, se destaca la necesidad

• In MM the optimal sequence or combination of the

  2019-05-07

  

  In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first

• In the APHRS survey most respondents

  2019-05-07

  

  In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate

• br Treatment and follow up recommendations for patients rece

  2019-05-07

  

  Treatment and follow-up recommendations for patients receiving aromatase inhibitors Conclusions and future directions It is evident that, in addition to BMD, clinical risk factors can greatly influence fracture risk. In addition to morbidity and mortality, fractures are associated with high he

• We hypothesized that CA with a lower energy setting W

  2019-05-06

  

  We hypothesized that CA with a lower why setting (20W) and strict monitoring of esophageal temperature at 39°C may prevent esophageal injury, even in patients with a BMI Methods Results Discussion Conclusion CA using ETM may reduce the incidence of esophageal injuries, even in patients w

• Despite our best efforts the

  2019-05-06

  

  Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po

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