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Importance of heart failure Acute decompensated heart failur
2019-05-24
Importance of lipoxygenase inhibitor failure Acute decompensated heart failure (ADHF) refers to a clinical condition of worsening HF with dyspnea, often with evidence of fluid overload [1]. This is generally triggered by 1 of the 4 main factors: atrial fibrillation, anemia, hypertension, and medic
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dofetilide Introduction Multiple myeloma MM is the most freq
2019-05-24
Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca
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br Epigenetic regulation of genes involved in hepatic lipid
2019-05-24
Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl
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br In Anand Bhopal s discussion March
2019-05-24
In Anand Bhopal\'s discussion (March, 2015) of health inequalities, social determinants of health, and advocacy for social change in health care in the 21st century, we were disappointed to see little recognition of the branch of medicine that pilocarpine hydrochloride epitomises “societal doctor
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br OPG RANK and RANKL contribute to the
2019-05-23
OPG, RANK and RANKL contribute to the vicious cycle established between tumour BIBF1120 and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several argum
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Introduction The World health organization WHO defines acute
2019-05-23
Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line
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niclosamide Holter ECG monitoring was performed after the pa
2019-05-23
Holter ECG monitoring was performed after the patient consumed 180mL of sake (alcohol) each night in both the DDD-R and DDD-CLS modes. The mean HR in the DDD-CLS mode (68bpm) was similar to that (71bpm) in the DDD-R mode, but during sleep, the atrial pacing ratio (43.2%) in DDD-CLS was significantly
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The exhibited efficacies of bone targeting treatments in pha
2019-05-23
The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b
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br Conclusions br Disclosures br Funding Sources
2019-05-23
Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r
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Los v nculos que el ensayista conserv con los
2019-05-23
Los vínculos que el ensayista conservó con los intelectuales mexicanos fueron profusos y perdurables, en tanto continuaron hasta sus últimos años de vida, aun durante su estadía en la Cuba revolucionaria de principios de los años sesenta. Así, en 1959 inició lo que Ángel Rama denominó el ciclo cuban
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Case report A year old Caucasian male who was evaluated
2019-05-23
Case report A 76 year-old Caucasian male who was evaluated in an emergency department due to headache in May 2001 and was found to have a right parietal subdural hematoma (SDH). Baseline blood work revealed thrombocytopenia of 50×109/L. His SDH was managed with surgical evacuation with full recover
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br After several decades of
2019-05-23
After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked
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Un tercer gui n si acaso el m
2019-05-22
Un tercer guión, si acaso el más inquietante de los tres, podría hallarse en la banda de cuatro críticos literarios consagrados AK Bioluminescence Cytotoxicity Assay Kit la obra de Archimboldi, el gran autor que Bolaño introduce en la novela 2666. La narración capta una muestra episódica del modo d
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This week delegates are gathered in Abu Dhabi
2019-05-22
This week, delegates are gathered in Abu Dhabi, United Arab Emirates, for the . A large portion of the programme will be dedicated to global progress on demand reduction measures laid out in WHO\'s (FCTC), which celebrated its 10th birthday last month. Adopted at the 56th World Health Assembly in 2
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br Case report A year
2019-05-22
Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara
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