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Programmed death ligand PD L expression is a characteristic
2019-06-27
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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All patients engrafted patient Patient developed secondary g
2019-06-27
All patients engrafted; 1 patient (Patient 6) developed secondary graft rejection following an A antigen mismatched graft from a male sibling and went on to receive a VUD HSCT with a female donor. There were no major conditioning related toxicities. Bacterial infections occurred in 6 patients prior
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L-Kynurenine br Risk of bleeding complications with dual ant
2019-06-27
Risk of bleeding complications with dual antiplatelet agents Dual antiplatelet therapy (DAPT) with combined aspirin and clopidogrel has become a standard treatment after percutaneous coronary intervention (PCI). Recent studies have examined the impact of such therapy on the incidence of bleeding
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Close inspection of the tumor matrix on
2019-06-27
Close inspection of the tumor matrix on the initial and subsequent 5 month radiographs (Fig. 7), shows an atypical appearance for osteoid matrix that adenosine deaminase may more closely resemble chondroid matrix. The matrix appears to display a linear dense lace-like pattern (Fig. 8). Of the only
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Effect of atorvastatin in modulation and protection of cardi
2019-06-27
Effect of atorvastatin in modulation and protection of cardiomyocyte ischemia and inflammatory phenomena (identified as a decline in perioperative CRP, hs-cTnT, and CPK-MB levels) [15,25–27] was not confirmed in the PROFACE trial. Because of no significant differences in the clinical preoperative or
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The congruence between BrS and ERS
2019-06-27
The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope
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Competing pressures for resources across sectors however mea
2019-06-27
Competing pressures for resources across sectors, however, mean that increasing the proportion of resources for health will be difficult. Efficiency gains in the health sector could help to make the case for more investment. Countries need to tackle major sources of inefficiency by doing more of the
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El caso argentino sobre la literatura fant
2019-06-27
El caso argentino sobre la literatura fantástica puede ser interpretado de modo similar al de Mukarovsky, GW1929 propósito de la obra de arte como hecho semiológico (estético/social): por un lado, se encuentra el signo poético, que Macedonio y Borges recuperan en la obra literaria mediante sus cuent
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br Transici n y representaci n Qu pas
2019-06-27
Transición y representación ¿Qué pasó con esa idea del campesino nacional, anacrónico y en conflicto con la modernidad en el momento posrevolucionario? Su reinscripción como una idealización coincide con los pactos de transición de régimen. A la vez, la participación militar de los campesinos com
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Para finalizar focaliza se o hospital l
2019-06-27
Para finalizar focaliza-se o hospital, lócus de embate desta pesquisa, e recorre-se aos direcionamentos de Donadone, em estudo envolvendo consultores e gerentes no país. Afirma o autor que “[…] é possível visualizar um processo de guerra cultural onde MK-4827 visão financeira da empresa se encontra
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En las relaciones pol ticas tradicionales mapuche el longko
2019-06-27
En las relaciones políticas tradicionales mapuche, el longko o autoridad tuvo la función de repartir las tierras, prerrogativa que perdió con los desplazamientos y las reducciones, situación que en unión al hecho de que los distintos gobiernos regidos por la intención del trato igualitario para los
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Este reconocimiento marca un rasgo distintivo de
2019-06-27
Este reconocimiento marca un rasgo distintivo de la reticente postura de Daniel Mato 6 his adoptar el nombre de ecl como campo de estudio. De manera consecuente, la mitad de las secciones de la antología están abocadas a la reflexión sobre los estudios culturales, el culturalismo, la crítica y el pa
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Introduction Acute erythroleukemia AEL is a rare subtype of
2019-06-27
Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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Analyses such as those used
2019-06-27
Analyses such as those used by Burke and colleagues rely on periodic cross-sectional surveys that are not linked to available or civic registration and vital statistics databases. These surveys are also limited by the inevitable time lag between analyses and feedback to health systems and policy mak
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Case report A year old
2019-06-26
Case report A 76 year-old Caucasian male who was evaluated in an emergency department due to headache in May 2001 and was found to have a right parietal subdural hematoma (SDH). Baseline blood work revealed thrombocytopenia of 50×109/L. His SDH was managed with surgical evacuation with full recover
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