In the Hedgehog signaling pathway cholesterol is required to

2022-01-03

In the Hedgehog signaling pathway, cholesterol is required to activate SMO (Cooper et al., 2003), the downstream target of PTCH1. A previous study (Bidet et al., 2011) reported that Patched expression in yeast BAY 87-2243 increased extrusion of a fluorescent boron dipyromethanene sterol derivative